SC 57461
CAS No. 423169-68-0
SC 57461 ( SC 57461A )
Catalog No. M14440 CAS No. 423169-68-0
A potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 87 | Get Quote |
|
10MG | 140 | Get Quote |
|
25MG | 282 | Get Quote |
|
50MG | 444 | Get Quote |
|
100MG | 651 | Get Quote |
|
200MG | Get Quote | Get Quote |
|
500MG | Get Quote | Get Quote |
|
1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSC 57461
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NoteResearch use only, not for human use.
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Brief DescriptionA potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM).
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DescriptionA potent and selective inhibitor of LTA4 hydrolase (LTA4H) with IC50/Ki of 5 nM/23 nM; inhibits calcium ionophore-induced LTB(4) production in human whole blood (IC50=49 nM), no effect on production of the cyclooxygenase metabolite thromboxane B(2); orally active in vivo.Irritable Bowel Syndrome Discontinued
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SynonymsSC 57461A
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PathwayOthers
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TargetOther Targets
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RecptorOther Targets
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Research AreaOther Indications
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IndicationIrritable Bowel Syndrome
Chemical Information
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CAS Number423169-68-0
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Formula Weight363.88
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Molecular FormulaC20H25NO3.HCl
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(O)CCN(C)CCCOC1=CC=C(CC2=CC=CC=C2)C=C1
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Chemical Name3-((3-(4-benzylphenoxy)propyl)(methyl)amino)propanoic acid hydrochloride
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Askonas LJ, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):577-82.
2. Kachur JF, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):583-7.
3. Penning TD, et al. J Med Chem. 2002 Aug 1;45(16):3482-90.
2. Kachur JF, et al. J Pharmacol Exp Ther. 2002 Feb;300(2):583-7.
3. Penning TD, et al. J Med Chem. 2002 Aug 1;45(16):3482-90.
molnova catalog
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